Inhibitory loop robustly induces anticipated synchronization in neuronal microcircuits

Fernanda S. Matias, Leonardo L. Gollo, Pedro V. Carelli, Claudio R. Mirasso and Mauro Copelli

We investigate the synchronization properties between two excitatory coupled neurons in the presence of an inhibitory loop mediated by an interneuron. Dynamic inhibition together with noise independently applied to each neuron provide phase diversity in the dynamics of the neuronal motif. We show that the interplay between the coupling strengths and the external noise controls the phase relations between the neurons in a counterintuitive way. For a master-slave configuration (unidirectional coupling) we find that the slave can anticipate the master, on average, if the slave is subject to the inhibitory feedback. In this nonusual regime, called anticipated synchronization (AS), the phase of the postsynaptic neuron is advanced with respect to that of the presynaptic neuron. We also show that the AS regime survives even in the presence of unbalanced bidirectional excitatory coupling. Moreover, for the symmetric mutually coupled situation, the neuron that is subject to the inhibitory loop leads in phase.

The whole paper is available here.

NeuroCineMat
Featuring this week:
Newsletter

Stay informed on our latest news!



Previous issues

Podcast A Matemática do Cérebro
Podcast A Matemática do Cérebro
NeuroMat Brachial Plexus Injury Initiative
Logo of the NeuroMat Brachial Plexus Injury Initiative
Neuroscience Experiments System
Logo of the Neuroscience Experiments System
NeuroMat Parkinson Network
Logo of the NeuroMat Parkinson Network
NeuroMat's scientific-dissemination blog
Logo of the NeuroMat's scientific-dissemination blog