Estimating the distance to a hereditary graph property

Carlos Hoppen, Yoshiharu Kohayakawa, Richard Lang, Hanno Lefmann and Henrique Stagni

Given a family of graphs "F", we prove that the distance to being induced "F"-free is estimable with a query complexity that depends only on the bounds of the Frieze-Kannan Regularity Lemma and a Removal Lemma for "F".

Dopamine Modulates Delta-Gamma Phase-Amplitude Coupling in the Prefrontal Cortex of Behaving Rats

Victoria Andino-Pavlovsky, Annie C. Souza, Robson Scheffer-Teixeira, Adriano B. L. Tort, Roberto Etchenique and Sidarta Ribeiro

Dopamine release and phase-amplitude cross-frequency coupling (CFC) have independently been implicated in prefrontal cortex (PFC) functioning. To causally investigate whether dopamine release affects phase-amplitude comodulation between different frequencies in local field potentials (LFP) recorded from the medial PFC (mPFC) of behaving rats, we used RuBiDopa, a light-sensitive caged compound that releases the neurotransmitter dopamine when irradiated with visible light. LFP power did not change in any frequency band after the application of light-uncaged dopamine, but significantly strengthened phase-amplitude comodulation between delta and gamma oscillations. Saline did not exert significant changes, while injections of dopamine and RuBiDopa produced a slow increase in comodulation for several minutes after the injection. The results show that dopamine release in the medial PFC shifts phase-amplitude comodulation from theta-gamma to delta-gamma. Although being preliminary results due to the limitation of the low number of animals present in this study, our findings suggest that dopamine-mediated modification of the frequencies involved in comodulation could be a mechanism by which this neurotransmitter regulates functioning in mPFC.

Ernst W. Hamburger: a life dedicated to promoting science

Video on the researcher and science popularizer Ernst W. Hamburger, produced by the RIDC NeuroMat, with support from FAPESP.

"The Arms of Nildo and Rony:" a NeuroMat story

A professional motorcyclist and a surgeon meet up at the waiting room of a physiotherapy clinic. They share a common story: rehabilitation after a traumatic brachial plexus injury. Their fate is somehow similar to the one of a famous soccer player who, after a serious lesion, must attend therapy sections to learn again how to play, after a period of recovery. These stories are the guiding narratives of a newly released educational material for patients, caregivers and health professionals, the illustrated magazine "The Arms of Nildo and Rony."

Could physical therapy be the future of specialised Parkinson’s care in Brazil?

Parkinson’s Life is an online ‘lifestyle’ magazine for people affected by Parkinson’s disease. Last month NeuroMat's AMPARO initiative was recognized as an outstanding initiative inside Brazil to promote collaboration between people with Parkinson’s and health professionals, in order to face clinical challenges via online lectures to improve the quality of life for people living with Parkinson’s. As an excerpt, we can read:

"Although there is a clear deficit regarding specialised Parkinson’s care in our country, I would like to highlight the good research centres in Brazil, such as the AMPARO network, developed in 2016 by the Research, Innovation and Dissemination Centre for Neuromathematics. The network was developed to promote collaboration between people with Parkinson’s and health professionals, in order to face clinical challenges via online lectures to improve the quality of life for people living with Parkinson’s."Parkinson’s Life website, 28/01/2018. (In English)




O Centro de Pesquisa, Inovação e Difusão em Neuromatemática está sediado na Universidade de São Paulo e é financiado pela FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo).


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