Video: Inside the brain

Movie on the exhibition "Por dentro do cérebro", at the University of São Paulo.

Production: Giulia Ebohon.

Coupled variability in primary sensory areas and the hippocampus during spontaneous activity

Nivaldo A. P. de Vasconcelos, Carina Soares-Cunha, Ana João Rodrigues, Sidarta Ribeiro and Nuno Sousa

The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.

Can somatosensory electrical stimulation relieve spasticity in post-stroke patients? A TMS pilot study

Peres A.S.C., Souza V.H., Catunda J.M.Y., Mazzeto-Betti K.C., Santos-Pontelli T.E.G., Vargas C.D., Baffa O., de Araújo D.B., Pontes-Neto O.M., Leite J.P. and Garcia M.A.C.

Evidence suggests that somatosensory electrical stimulation (SES) may decrease the degree of spasticity from neural drives, although there is no agreement between corticospinal modulation and the level of spasticity. Thus, stroke patients and healthy subjects were submitted to SES (3 Hz) for 30' on the impaired and dominant forearms, respectively. Motor evoked potentials induced by single-pulse transcranial magnetic stimulation were collected from two forearm muscles before and after SES. The passive resistance of the wrist joint was measured with an isokinetic system. We found no evidence of an acute carry-over effect of SES on the degree of spasticity.

NeuroMat's report of activities: research, technology transfer and dissemination

Stochastic models for biological neural networks. “Statiscian brain” conjecture. High-performance computing. Open-source, free softwares. New directions for early diagnosis of Parkinson’s Disease. Brachial-plexus-injury initiative. Wikipedia. The Research, Innovation and Dissemination Center for Neuromathematics (RIDC NeuroMat) has released the report of activities for 2015-2017, to be assessed by the São Paulo Research Foundation (FAPESP) international evaluation committee.

Event addresses the mathematical culture, diagnostics and perspectives

On May 16, the meeting "Numeracy in Brazil: diagnoses and perspectives", promoted by the Research, Innovation and Dissemination Center for Neuromathematics (RIDC NeuroMat) took place at University of São Paulo (USP). This event was part of the Brazilian Mathematics Biennium and had the support of the São Paulo Research Foundation and the University of São Paulo School of Education.

According to the professor Dr. Fernando Paixão, NeuroMat's coordinator of scientific diffusion and one of the event's organizer, the objective was to discuss about the mathematical culture, especially in Basic Education. Carol Gama, Oxigênio, 06/13/2017. (In Portuguese)




O Centro de Pesquisa, Inovação e Difusão em Neuromatemática está sediado na Universidade de São Paulo e é financiado pela FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo).


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