The effect of magnetization of natural rubber latex coated magnetite nanoparticles on shear wave dispersion magneto-motive ultrasound

Saeideh Arsalani, Soudabeh Arsalani, Yaser Hadadian, Diego Ronaldo Thomaz Sampaio, Oswaldo Baffa, Theo Zeferino Pavan and Antonio Adilton Oliveira Carneiro

The shear wave dispersion magneto-motive ultrasound (SDMMUS) method was recently developed to analyze the mechanical properties of a viscoelastic medium. This technique is based on the interaction of magnetic nanoparticles (MNPs) with an external magnetic field to generate a shear wave within the medium labeled with MNPs. The propagation of this wave provides information about viscoelastic properties of the medium. In the previous work Arsalani et al. magnetite NPs were synthesized by co-precipitation method coated with natural rubber latex (NRL). In order to investigate the effect of NRL on the size and magnetization of MNPs, different amount of NRL, 0 μL, 100 μL, and 800 μL of a stock solution of NRL, were used during the synthesis process. The results showed that MNPs prepared with 800 μL of NRL, named as MNPs-800NRL, had the smallest size and highest magnetization. In the present paper, the main goal is to investigate if the MNPs-800NRL having the highest magnetization is also the best option for SDMMUS experiments among the others. All experiments were performed using gelatin tissue mimicking phantoms labeled with the aforementioned MNPs. Two factors including core size and magnetization were considered and based on the observed results the effect of magnetization was more prominent than the core size on the induced displacements. MNPs coated with a thicker NRL shell having the highest magnetization value enhanced the sensitivity and signal to noise ratio in SDMMUS. Different concentrations of this optimized MNPs were also examined to investigate the lowest possible concentration for observing shear waves in the SDMMUS technique.

Highlights of the NeuroMat report of activities

The Research, Innovation and Dissemination Center for Neuromathematics (RIDC NeuroMat) released its sixth report of activities in August. The report comprises activities in research, innovation and dissemination from January to August, 2019. The RIDC NeuroMat was created in 2013 by the São Paulo Research Foundation (FAPESP) and is coordinated by Antonio Galves.

Unilateral Brachial Plexus Lesion Impairs Bilateral Touch Threshold

Bia Lima Ramalho, Maria Luíza Rangel, Ana Carolina Schmaedeke, Fátima Smith Erthal and Claudia D. Vargas

Unilateral brachial plexus injury (BPI) impairs sensory and motor functions of the upper limb. This study aimed to map in detail brachial plexus sensory impairment both in the injured and the uninjured upper limb. Touch sensation was measured through Semmes-Weinstein monofilaments at the autonomous regions of the brachial plexus nerves, hereafter called points of exclusive innervation (PEIs). Seventeen BPI patients (31.35 years±6.9 SD) and 14 age-matched healthy controls (27.57 years±5.8 SD) were tested bilaterally at six selected PEIs (axillary, musculocutaneous, median, radial, ulnar, and medial antebrachial cutaneous [MABC]). As expected, the comparison between the control group and the brachial plexus patients' injured limb showed a robust difference for all PEIs (p ≤ 0.001).

Mean field limits for nonlinear spatially extended Hawkes processes with exponential memory kernels

J. Chevallier, A. Duarte, E. Löcherbach and G. Ost

We consider spatially extended systems of interacting nonlinear Hawkes processes modeling large systems of neurons placed in and study the associated mean field limits. As the total number of neurons tends to infinity, we prove that the evolution of a typical neuron, attached to a given spatial position, can be described by a nonlinear limit differential equation driven by a Poisson random measure. The limit process is described by a neural field equation. As a consequence, we provide a rigorous derivation of the neural field equation based on a thorough mean field analysis.

Statistical model selection in the brain and electrophysiological signatures

The NeuroMat scientific dissemination has released a video that presents the work of research Fernando Najman in the NeuroMat research team. This video was produced with an immersive technique, so it is possible to wander around as Najman presents on various aspects of his work.

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